From the author: Afobazole reviews forum. Instructions for use. Fabomotizol. Clinical review of drug prescription cases. Afobazole for anxiety, depression, neurosis, VSD, insomnia, stress, tachycardia, gastritis, IBS, OCD, PTSD. Added reviews from patients who took Afobazol. The reviews are different: from brightly positive to neutral and even negative. My comments 2018, 2019, 2020, doctor's reviews. Help from a psychiatrist in Moscow. Novopassit or Afobazol? Persen or Afobazol? Stresam or Afobazol? What's better? Overdose. With alcohol. When driving. For details, see the instructions for the drug! Pharmstandard company. In neurology. Experience of using the drug "Afobazol" in the psychotherapy room of the Moscow city clinic No. 120. Review of clinical cases for 2009–2010. This article provides brief descriptions of eight clinical cases of observation and treatment of patients using Afobazole in combination therapy. Case one. Patient A., born in 1978, married, does not work. Diagnosis: Generalized anxiety disorder syndrome (F 41.1 according to ICD-10) in a patient who had previously used drugs—heroin. Comorbid diseases: viral hepatitis C; HIV infection. The patient was prescribed combination pharmacotherapy: Rexetine (antidepressant) 20 mg. per day;—Relium (benzodiazepine tranquilizer) 5 mg. twice a day;—Afobazole 1 tablet. three times a day. Psychotherapy: explanatory in nature. Within a week, the patient experienced a marked improvement in well-being: panic attacks disappeared, the level of “free-floating” anxiety decreased, sleep quality was restored, and mood improved. The patient was then transferred to maintenance treatment with Rexetine and Afobazole . Case two. Patient B., born in 1952, married, retired. Diagnosis: Persistent somatoform pain disorder (F 45.4 according to ICD-10); tension headache; anxiety-depressive syndrome. At the beginning of therapy, the patient was prescribed Amitriptyline (antidepressant) 30 mg. per day and Teraligen (mild antipsychotic) 5 mg. three times a day. Within a week, resistance to therapy was discovered due to the constant psychotraumatic situation in the family. In addition, the patient complained of constant dry mouth, which further asthenized her. As a result, it was decided to cancel the previous therapy and prescribe Afobazol, 2 tablets. three times a day, as a result of which a moderate anti-anxiety effect was achieved with a complete absence of side effects. In addition to psychopharmacotherapy, sessions of explanatory psychotherapy were conducted with the patient; training in exercises according to A. Sitel aimed at relaxing the muscles of the head and neck; in the physiotherapy department, The patient underwent ten sessions of massage of the collar area. As a result of this combination therapy, the patient’s well-being significantly improved; psychophysiological conditions have been created to solve the problem in the family. Case three. Patient V., born in 1986, unmarried, office worker. Diagnosis: Somatoform dysfunction of the autonomic nervous system (F 45.3 according to ICD-10); irritable gastrointestinal syndrome. Prescribed: Afobazole 1 tablet. three times a day;—Trimedat (selective vegetative corrector of the gastrointestinal tract) 200 mg. three times a day.—ten sessions of auto-training and music therapy. As a result of the treatment, the patient’s well-being significantly improved within three weeks. Occasionally, against the background of psycho-emotional stress, spasmodic pain occurred in the abdomen. When the dosage of Afobazole was increased to two tablets three times a day, no pain occurred (psychosomatic anxiety was relieved). Case four. Patient G., born in 1989, single, university student. Diagnosis: Anxiety-depressive disorder (F 41.2 according to ICD-10); anxious-avoidant personality traits. A feature of this clinical case was that the patient had pharmacophobia— extreme distrust of medicines with fear of “addiction” and“side effects”. In connection with this, the patient, after a session of explanatory psychotherapy, was prescribed Afobazol, 1 tablet. three times a day. Plus ten sessions of auto-training and music therapy. Over the next week, the patient’s well-being improved significantly; The therapeutic alliance was strengthened. This made it possible to double the dose of Afobazole (2 tablets three times a day) and prescribe a herbal antidepressant—Deprim, 1 tablet. three times a day. Which led to a pronounced and lasting positive effect: anxiety and panic attacks were relieved; mood improved. Case five. Patient D., born in 1935, widow, pensioner. Diagnosis: Organic anxiety disorder (F 06.4 according to ICD-10). Considering the organically unfavorable basis for the occurrence of the disorder, the patient was prescribed Phenibut (a nootropic drug with a pronounced anti-anxiety effect) for 250 mg. three times a day. Additionally: ten sessions of auto-training and music therapy. During the first three days, the patient noted discomfort in the epigastric region (abdominal area) when using the drug. Phenibut was discontinued and replaced with Afobazole, 2 tablets. three times a day. The effect was very moderate; no side effects occurred. As a result, after three weeks of therapy, the patient’s well-being improved positively. Case six. Patient E., born in 1982, married, housewife. Diagnosis: Somatization disorder (F 45.0 according to ICD-10). The patient was prescribed: Plizil (antidepressant) 20 mg. per day;—Afobazole 1 tablet. three times a day; ten sessions of auto-training and music therapy. As a result of three weeks of therapy, the patient’s well-being was completely normalized. Transferred to maintenance dosages of Plizil and Afobazole. Case seven. Patient Zh., born in 1960, married, housewife, disabled person of the second group “due to general illness.” Diagnosis: Recurrent depressive disorder (F 33.0 according to ICD-10), current depressive episode of moderate severity; anxiety syndrome. Doctor’s prescriptions:— Paxil (antidepressant) 30 mg. per day;—Afobazole 1 tablet. three times a day; sessions of explanatory and supportive psychotherapy. As a result of treatment, the patient’s condition improved: her mood improved, apathy and anxiety were relieved. She was transferred to maintenance therapy with Paxil and Afobazol. Case eight. Patient Z., born in 1989, unmarried, university student. Diagnosis: Post-traumatic stress disorder (F 43.1 according to ICD-10), dysphoric variant of the course. Feature of the case: severe degree of disorder—the patient experienced states of dysphoria at night (sad, angry tension) and, to relieve this discomfort, self-cut himself in the shoulder area. Physical pain significantly relieved mental pain. The situation was aggravated by codependency with her mother, jealousy of her man and her sister. Transfer of the patient: the doctor looked like his mother’s lover, which significantly complicated the formation of a therapeutic alliance. The doctor strongly recommended hospitalization for the patient, but the patient categorically refused. Initial therapy included: - Cymbalta (antidepressant) 60 mg. per day;—Sanval 10 mg. at night;—Afobazole 2 tablets. four times a day; - sessions of explanatory psychotherapy. For two months, the patient noted an improvement in well-being; then decompensation of the disorder reappeared. The next stage of therapy included replacing the previous drugs with the following: - Amitriptyline (antidepressant) 50 mg. per day; Neuleptil (neuroleptic) 5-10 drops (5-10 mg) at night; Cyclodol (antipsychotic corrector) 2 mg. at night;—Phenazepam (benzodiazepine tranquilizer);—directive psychotherapy. Only against the background of this treatment did the patient’s well-being improve; a stable mental state emerged. Conclusion: non-benzodiazepine tranquilizer Afobazole, used in a clinic: 06/1/2010 The material is provided for informational purposes. For consultation, please contactdoctor.------------------------------------------------ -------------------------------------------------- ---------------PS As an afterword, I would like to explain why many doctors (including me, in 2010) prescribe synthetic drugs! Reasons for choosing an allopathic drug for a doctor , and not homeopathic, lie in different planes.1) A modern doctor does not receive even the basic fundamentals of homeopathy in medical school. Accordingly, I am not familiar with its capabilities in curing diseases. 2) Prejudice towards homeopathy among representatives of the so-called. classical medical school. This is due to the dominance of the allopathic medical model (treatment by the opposite). 3) Commercial interests of pharmaceutical companies that are not interested in treating patients, but are only interested in increasing sales of their patented drugs. Doctors are under constant pressure from scientific employees of various institutes who are engaged by pharmaceutical corporations: when giving lectures and making reports, representatives of science always focus on the medicine that is being promoted by the inviting pharmaceutical company. Moreover, in this struggle of interests, even... . doctor! Allopath or homeopath, it doesn’t matter! A doctor, from the point of view of pharmaceutical businessmen, is just an annoying intermediary between the manufacturer-distributor and the consumer (patient). The desired model that businessmen dream about: they pay for advertising on TV and deliver the required amount of patented drugs to the pharmacy, the patient sees the advertisement on TV, goes to the pharmacy and buys their drug! Oh, they count the profits! But for now, pharmaceutical companies still cannot do without a doctor. Therefore, they focus their information influence on him as well. Being under pressure from biased authorities of academic medicine, an ordinary ordinary doctor treats his patients with recommended remedies. Including Afobazol. -------------------------------------------------- -------------------------------------------------- Also, I would like to add a question from the Internet: “Afobazol or GrandaxinDear doctors! Share your experience! Which drug is more effective for vegetative dystonia, anxiety syndrome. And the prescription regimen for Grandaxin. I can’t find it anywhere, everywhere it is written that the effect occurs after using Grandaxin for 2 weeks How many weeks should I take it and is it necessary to take repeated courses? I found an article that Afabazole is more effective, is this true? “My answer: 1) Grandaxin and Afobazole really belong to the same group (tranquilizers), but their mechanism of action is very different!2 ) The effect of both Afobazole and Grandaxin appears IMMEDIATELY! 3) With a significant disorder, the effect of these drugs may be INsignificant! 4) The method of choice, in this case, is homeopathy. Medicines are prescribed only by a doctor with a special education! (November, 2018).------------------------------------------------ -------------------------------------------------- ---------------------------- Feedback from the psi-forum (2019): "..., for my father, afobazole for myasthenia, one neurologist I prescribed it. It’s such ignorance: tranquilizers for myasthenia gravis are prohibited, except for one, but not afobazole. And then the anxiety increased even more. Until I realized. “My comment: 1) What exactly did I want to “cure.” “A neurologist prescribing Afobazole for myasthenia gravis remains a mystery. 2) Deterioration in myasthenia gravis is not uncommon. It is necessary to look at all factors, including ALL medications taken. Information regarding the use of coffee and tea by patients with anxiety disorders. Important! Coffee and tea, so-called. “energy drinks” are psychostimulants, because contain the alkaloid Caffeine. ANY psychostimulation “pulls out” anxiety! Accordingly, these drinks are contraindicated for patients with anxiety disorders, insomnia, and agitation. Patients who are advised by a doctor to stop drinking tea and coffee are surprised and give all sorts of arguments,.